Chromosome abnormalities in patients with hairy cell leukemia
نویسندگان
چکیده
منابع مشابه
Hairy cell leukemia is characterized by clonal chromosome abnormalities clustered to specific regions.
Cytogenetic analysis was performed on B-cell mitogen-stimulated cells from 36 patients with symptomatic hairy cell leukemia. Evaluable metaphases were achieved from 30 patients, and (67%) showed clonal abnormalities. Recurrent chromosomal aberrations involving chromosomes 1, 2, 5, 6, 11, 19, and 20 were found. The abnormalities were mostly deletions and inversions, whereas translocations and nu...
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ژورنال
عنوان ژورنال: Cancer
سال: 1978
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(197804)41:4<1374::aid-cncr2820410422>3.0.co;2-5